Peptides are molecules consisting of two or more amino acids linked by a chemical bond. Peptides can be short or long, and they can be naturally occurring or synthetic. In the body, peptides are used to regulate many different processes. They are also used in medicine to treat a wide range of diseases.
Most peptides have one or more functions: they can serve as hormones, neurotransmitters, cytokines (signaling molecules involved in immune responses), growth factors (signaling proteins that control cell growth), and cellular messengers. These functions help regulate metabolism, blood pressure, and circulation; they also play essential roles in other bodily functions such as digestion, reproduction, and immunity.
Peptides are a group of compounds that consist of amino acids. They are the building blocks of proteins and have many different functions in the body. Some peptides are responsible for communication between cells and tissues in your body, while others help fight infection or heal wounds.
The peptides used in hormone replacement therapy (HRT) may also improve muscle growth, strength, and performance. HRT with testosterone pellets can treat male hypogonadism, which affects 1 out of 10 men over 30 years old. This condition causes low libido, erectile dysfunction, and decreased muscle mass and strength.
CJC-1295 stimulates HGH secretion and can provide a steady increase of HGH (Human Growth Hormone) with minimal effect on cortisol and prolactin levels. This means increased protein synthesis thus promoting growth and fat loss simultaneously. Ipamorelin mimics ghrelin and binds to the ghrelin receptor (or GH secretagogue receptor, GHSR) in the brain, thereby selectively stimulating the release of GH from the pituitary gland. This results in increased plasma GH levels, which affect many biological processes. Unlike other GH-releasing peptides, Ipamorelin only stimulates GH release in a manner very similar to that of growth hormone-releasing hormone. This combination results in a great aid for sleep, energy, stamina, and recovery benefits.
CJC-1295/Ipamorelin reduces recovery time and increases lean muscle mass. This is a great peptide to help improve workouts and reduce body fat percentage.
Tesamorelin is the only secretagogue that is approved for abdominal fat loss, compared to CJC-1295/Ipamorelin. Men who add weight in the belly (abdomen) should be directed to use tesamorelin over CJC-1295/Ipamorelin. The dose of tesamorelin ranges from 500mcg to 2mg, with nightly subcutaneous injections for five nights in a row. Patients should stop taking this for two consecutive. Results vary based on diet and exercise routine. However, patients can decrease body fat percentage by 3%-9% points over six to twelve months.
CJC-1295 comes in various formulations, including troches (tro-keys) and subcutaneous injection. Subcutaneous injection of peptides will always provide superior absorption and results compared to oral ingestion. Many patients are unable to self-inject and opt for troches. Patients should double or triple the dose when using troches, as most of the medication is lost in absorption. Another advantage of using troches is the ability to compound CJC-1295 with another peptide, like AOD-9604.
The dose for CJC-1295 and Tesamorelin depends on the route of administration, height, weight, and gender of the patient. The table below provides a guideline for dosing CJC-1295 and Tesamorelin. However, your provider should help guide your dosing.
| Peptide | Male Dose | Female Dose | Dose Schedule |
|---|---|---|---|
| CJC-1295/Ipamorelin Injection | 200/200mcg – 400/800mcg | 200/200mcg – 500/500mcg | 5 nights on 2 nights off |
| CJC-1295/Ipamorelin/IGF1 LR3 | 500/375/25mcg | 125/280/18mcg – 200/400/20mcg | 5 nights on 2 nights off |
| CJC-1295/Ipamorelin Troche | 600/600mcg | 300/300mcg | 5 nights on 2 nights off |
| CJC-1295/Ipamorelin/AOD9604 Troche | 300/200/300mcg | 300/200/300mcg | 5 nights on 2 nights off |
| Ipamorelin/Tesamorelin Injection | 100/200mcg – 125/625mcg | 100/200mcg – 125/625mcg | 5 nights on 2 nights off |
| Tesamorelin Injection | 500mcg – 2000mcg | 500mcg – 2000mcg | 5 nights on 2 nights off |
CJC-1295 / Ipamorelin is considered a long-term therapy, over months. All growth hormones take months before the benefit is appreciated.
In the first 3 months we anticipate:
In months 4-6 we anticipate:
Patients should anticipate staying on Sermorelin or Tesamorelin for 6-12 months at a minimum to reach body fat reduction goals of 3-9%. Of course, this requires that patients balance their diet and exercise. Patients need to reduce their intake of sugar and high-fat food items and restrict carbs throughout the day, except after working out at the gym. This includes using casein protein at night before bed and whey or plant protein after regular workouts. Workouts should be focused on cardio, with low weights and high repetitions when starting CJC-1295 or tesamorelin. After three months, patients will need to switch to reduced cardio, with high weights and low repetitions. Patients who require weight loss should start with semaglutide before switching to CJC-1295 or Tesamorelin.
Ordering CJC-1295 or Tesamorelin as an injectable or troche has never been easier. Mobile Care Health offers dozens of formulations of CJC-1295/Ipamorelin and Tesamorelin, including IGF1LR3, to improve insulin sensitivity. “We currently offer telehealth for peptides in 28 states and counting,” said Dr Jake Weinstein, Nurse Practitioner and owner of Mobile Care Health. He added, “Patients are taking control of their health, now, more than ever, including non-traditional medicine. This means patients seek peptide therapy, PRP, and sexual health, from providers who understand peptides and other non-mainstream solutions. People want to improve the quality of their life and prevent disease, not just have an annual exam that offers little benefit.” If you are interested in peptide therapy, contact Mobile Care Health for a consult.
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