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Is Semaglutide Safe for Your Health Journey?

A person with long dark hair sits in bed wearing pajamas, looking at a syringe.

Key Takeaways:

  • Semaglutide is FDA-approved for weight management and to treat type 2 diabetes. This demonstrates effectiveness and safety when used under medical supervision.
  • Potential side effects range from common digestive issues like nausea to serious risks such as pancreatitis, requiring medical supervision.

In recent years, semaglutide has gained popularity as a weight management medication under the brand names Wegovy (FDA-approved) and Ozempic (off-label use). Originally developed as a treatment for type 2 diabetes, semaglutide has shown impressive weight loss results in studies with diabetics and in a medical study of adults with obesity (BMI ≥30) or who are overweight (BMI ≥27) and also had an additional weight-related medical issue.

At Mobile Care Health, we know that your health journey is about more than just numbers on a scale. We’re here to have an open, honest conversation about how treatments like compounded semaglutide with B12 could enhance your overall well-being. Our approach is all about understanding you—your lifestyle, your goals, and your concerns. Are you curious about whether compounded semaglutide could be a positive step for you? Let’s start with how it works.

The science behind semaglutide: How does semaglutide work?

Semaglutide is an injectable medication that mimics GLP-1, a hormone that regulates appetite and food intake. When introduced to your body, it activates GLP-1 receptors in your brain, signaling satiety and reducing hunger. This sophisticated mechanism helps you consume less without feeling deprived, making it easier to adhere to a nutritious eating plan tailored to your unique health profile.

In terms of diabetes management, semaglutide helps lower blood sugar levels by stimulating insulin production and reducing glucose production in the liver. This dual action makes it an attractive option for those managing both weight and diabetes, allowing for a more integrated approach to your overall health. 

To help you understand how semaglutide measures against other treatments, here’s a quick comparison:

TreatmentEffectiveness in Weight ManagementDiabetes ManagementAdministration 
SemaglutideHighEffectiveWeekly injection
TirzepatideVery HighHighly EffectiveWeekly injection
Traditional Diabetes MedicationsLow to ModerateEffectiveVaries (oral/injection)
Lifestyle Changes AloneModerateModerately EffectiveN/A

A holistic approach to using semaglutide

Integrating semaglutide into your health journey is more effective when approached holistically. While semaglutide is helpful in weight management and controlling blood sugar levels, combining it with broader lifestyle changes, attentive medical supervision, and focusing on personal well-being can enhance its benefits and support your overall health.

  • Integrate lifestyle modifications. A balanced diet remains foundational, even with semaglutide’s appetite-regulating effects. Emphasizing nutrient-dense foods can help support your weight management goals and overall nutrition. Regular physical activity also plays a significant role. Additionally, staying well-hydrated supports bodily functions and can help alleviate some of the medication’s gastrointestinal side effects.
  • Focus on medical supervision. Regular check-ins with your doctor are essential to monitor the medication’s effectiveness and manage potential side effects. Your healthcare provider can help tailor your dosage and treatment plan based on your needs, ensuring the best possible outcomes. Addressing any side effects you experience with your provider allows for timely adjustments and can improve your overall comfort with the medication.
  • Prioritize personal well-being is important for overall success. Managing the emotional and psychological aspects of weight management and chronic disease is important. Incorporating stress management techniques, ensuring adequate sleep, and engaging in support systems can significantly impact your journey. Setting realistic goals and celebrating progress can motivate and reinforce positive changes.

By combining semaglutide with these holistic strategies, you can optimize the medication’s benefits and foster a more balanced and sustainable approach to your health.

What are common side effects of semaglutide?

Common side effects of semaglutide, including those identified by medications like Wegovy® and Ozempic®, primarily affect the digestive system. These side effects may include:

  1. Nausea – This is one of the most frequently reported side effects and may diminish as the body adjusts to the medication.
  2. Vomiting – Occasional but can occur as a result of nausea.
  3. Diarrhea – Loose stools or diarrhea is another common side effect, especially early in treatment.
  4. Constipation – Some people may experience the opposite, with difficulty passing stools.
  5. Abdominal pain – General discomfort or pain in the stomach area.
  6. Decreased appetite – Semaglutide is designed to regulate appetite, which may lead to an unintentional reduction in calorie intake.
  7. Indigestion (Dyspepsia) – This includes a feeling of fullness, bloating, or heartburn.

What are serious potential side effets of semaglutide?

Serious potential side effects of semaglutide, while less common, can pose significant health risks. Before proceeding with a medication regimen, you should always consult a healthcare professional like those at Mobile Care Health.  

Potential serious side effects include:

  • Pancreatitis – A serious inflammation of the pancreas, which can cause intense and persistent abdominal pain that may radiate to the back. It’s often accompanied by nausea and vomiting. This condition requires immediate medical attention to prevent complications.
  • Thyroid C-cell Tumors (including Medullary Thyroid Carcinoma – MTC) – Semaglutide has been associated with an increased risk of thyroid tumors in animal studies. However, it’s unclear if this applies to humans. Symptoms such as a lump in the neck, trouble swallowing, hoarseness, or shortness of breath should be evaluated by a doctor. People with a personal or family history of MTC or MEN2 should avoid using semaglutide.
  • Gallbladder problems – Semaglutide may increase the risk of gallbladder disease, including gallstones. Symptoms of gallbladder issues include sudden, sharp pain in the upper right side of the abdomen, nausea, vomiting, and jaundice (yellowing of the skin or eyes). If these symptoms occur, contact a healthcare provider promptly.
  • Kidney injury – Dehydration from excessive vomiting or diarrhea can lead to kidney damage or exacerbate existing kidney conditions. Symptoms such as decreased urine output, leg swelling, or extreme fatigue could indicate kidney issues.
  • Diabetic retinopathy complications – For those with Type 2 diabetes, rapid improvements in blood sugar control caused by semaglutide may worsen existing eye conditions like diabetic retinopathy. Symptoms such as blurred vision, floaters, or vision loss should be taken seriously and reported to an eye specialist as soon as possible.
  • Severe allergic reactions – Though rare, semaglutide may cause a serious allergic reaction known as anaphylaxis. Signs include rash, facial swelling, severe dizziness, and difficulty breathing. This is a medical emergency, and immediate treatment is necessary.

Is semaglutide safe for long-term use?

When considering semaglutide as part of your wellness journey, you might wonder about its safety for sustained use. Recent research offers valuable insights for those looking to incorporate this medication into their health plan. 

A study published in Nature Medicine followed participants for 104 weeks, revealing that semaglutide led to a significant weight reduction of 15.2% compared to 2.6% with a placebo. These findings suggest semaglutide can be effective for enduring weight management when used as part of a holistic health approach.

While the long-term benefits are encouraging, it’s important to be aware of potential adjustments your body might experience. The same study reported that 82.2% of semaglutide participants experienced some digestive changes, compared to 53.9% in the placebo group. We understand that adapting to a new medication can feel daunting. 

That’s why at Mobile Care Health, we’re committed to supporting you every step of the way. We work closely with you to develop strategies that minimize the discomfort that may come with taking compounded semaglutide, such as gradual dose adjustments and dietary modifications that align with your individual needs and preferences.

In general, who should not take semaglutide?

In general, semaglutide should not be taken by individuals with a personal or family history of medullary thyroid carcinoma (MTC) or those with Multiple Endocrine Neoplasia syndrome type 2 (MEN2), as semaglutide has been linked to an increased risk of thyroid tumors in animal studies. 

It is also not recommended for people with a known hypersensitivity to semaglutide or any of its components, as it may cause severe allergic reactions. Additionally, individuals with a history of pancreatitis should avoid using semaglutide, as the medication can increase the risk of this condition. 

Pregnant or breastfeeding women are generally advised against using semaglutide, as the potential effects on fetal development and breast milk are not fully understood. People with severe gastrointestinal issues, particularly those that involve delayed gastric emptying, may also need to avoid semaglutide due to its effect on slowing digestion. 

Consulting a healthcare provider is essential to determine if semaglutide is appropriate based on one’s medical history and conditions.

Personalized care and semaglutide safety at Mobile Care Health

Semaglutide offers promising benefits for weight management and type 2 diabetes control. Its efficacy in aiding weight loss and improving glycemic control has been well-documented. However, like any medication, it carries potential risks and side effects that need careful consideration.

The key to a successful health journey with semaglutide lies in a comprehensive approach—one that includes a thorough medical evaluation, lifestyle modifications, and ongoing monitoring. 

At Mobile Care Health, we believe your path to wellness deserves a custom-tailored approach. That’s why we’ve designed our compounded semaglutide with B12 program to adapt to your unique needs and aspirations. Ready to explore a new frontier in personalized healthcare? Connect with Mobile Care Health today for a free consultation with one of our providers to discuss your options and kickstart your journey towards your healthiest self.

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Clayton Evans

Clayton Evans is an IFA Certified Personal Trainer and IFA Certified Sports Nutritionist with over 5 years of experience in the health and fitness Industry. After years of struggling with his own health and fitness, Clayton lost over 30 lbs and started a career helping others achieve the best version of themselves. Clayton spent several years working with large corporate gyms developing fitness programs and working with Nutrition and Wellness Companies to improve a client’s overall health. His approach with clients is simple – small changes in fitness and diet that will have the largest impact and will fit into a client’s busy lifestyle.

Chad Antonson

Chad is a native of Colorado, growing up on the western slope. He moved to the Denver area in 2019 after working as a wild land firefighter through Job Corps. In his free time he enjoys hiking, skiing and traveling.

Brooke Young

Brooke is a skilled and compassionate Adult Nurse Practitioner with over 10 years of experience in healthcare and a passion for helping patients achieve optimal health and wellness. Brooke holds a Master of Science in Nursing with a specialization in adult health and gerontology from Maryville University of St. Louis. She completed post-graduate training in functional medicine through the Institute for Functional Medicine and obtained her NP board certification through the American Academy of Nurse Practitioners Credentialing Board in 2019. As a Nurse Practitioner, Brooke seeks to address the root causes of disease and treat the whole person, rather than just the symptoms. She believes in taking a personalized and holistic approach to each patient. She has special interests in helping patients heal from metabolic syndrome, achieve their weight loss goals, optimize fertility, and recover from complex chronic illness. In her free time, Brooke enjoys hiking, reading, rollerblading, cooking healthy meals, and spending time with her fun-loving husband and spirited toddlers. She is excited to partner with you on your health journey and support you in achieving your goals.

Kyle Christensen

Kyle is a career Firefighter/Paramedic with extensive experience in the Denver metro area. He holds a bachelors of Health and Exercise Science from CSU. Kyle enjoys weightlifting, skiing, boating, and all the outdoor activities Colorado has to offer.

Jacqueline Carbone

Jacqueline Carbone is a highly experienced nurse practitioner that specializes in providing her clients with holistic, evidenced based, compassionate care. She specializes in Mental health, ketamine assisted therapy and Migraines. She is board certified from the American Nurses Credentialing Center. Jacque has her post Masters certificate from University of Colorado in Psychiatric Mental Health and two master’s degrees—one in acute care/geriatric nursing and one as a clinical specialist in geriatrics—from Georgetown University. She has also completed a fellowship with Dr Arnaldo DeSilva a headache specialist. She is passionate about providing a holistic treatment plan for her clients.

Steve Ohl

Steve is a native of Colorado with bachelors in culinary nutrition. He worked as a classically trained chef, for over a decade. After chef life he shifted careers to join Mobile Care Health as our Operations Manager. Steve enjoys Crossfit, boating, road trips and camping.

Dr. Michael McGurren

Dr Michael McGurren was born and raised in Denver, Colorado. He graduated from Creighton University Medical School, and was the Chief Resident followed at Barnes-Jewish in St. Louis. He is board certified in Emergency Medicine and provides medical direction, as well as urgent care services for Mobile Care Health. In his free time he can be found sailing around the world, with a captains license and over 2500 nautical miles sailed. On shore he enjoys traveling with wife and pup Kylo in custom campervan.